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First-line treatment for CLL in the era of targeted therapy

Abstract In the decade since FDA approval of the first-generation Bruton’s tyrosine kinase (BTK) inhibitor ibrutinib, the treatment landscape for chronic lymphocytic leukemia (CLL) has transformed. Targeted agents, as monotherapy or in combination regimens, have decisively replaced chemoimmunotherap...

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Principais autores: Matthew S. Davids, Stephan Stilgenbauer, Constantine S. Tam
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2026-01-01
Serija:Blood Cancer Journal
Online dostop:https://doi.org/10.1038/s41408-025-01434-2
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