Acquired mutations in patients with relapsed/refractory CLL who progressed in the ALPINE study

Abstract: Some patients with chronic lymphocytic leukemia who develop progressive disease (PD) during covalent Bruton tyrosine kinase (BTK) inhibitor treatment acquire resistance mutations in BTK or PLCG2. Here, we report gene mutation data from paired baseline and PD peripheral blood samples from 5...

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Detalhes bibliográficos

Principais autores:	Jennifer R. Brown, Jessica Li, Barbara F. Eichhorst, Nicole Lamanna, Susan M. O’Brien, Constantine S. Tam, Lugui Qiu, Ruiqi Huang, Yang Shi, Adam Idoine, Tommi Salmi, Aileen Cleary Cohen, Mazyar Shadman
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2025-04-01
Colecção:	Blood Advances
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2473952925000473
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