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Synthesis, biological and computational evaluation of novel cyanomethyl vinyl ether derivatives

This work explores the biological evaluation of novel cyanomethyl vinyl ether derivatives as antiproliferative agents. Tubulin, crucial to microtubule structure and function, is a target for cancer therapies. In vitro cytotoxicity assessments revealed significant activity in SKOV3 ovarian carcinoma...

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Detalles Bibliográficos
Principais autores: Endika Martín-Encinas, María Fuertes, Samuel Delgado-Hernández, Fernando García-Tellado, David Tejedor, Concepción Alonso
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Pharmacology
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Acceso en liña:https://www.frontiersin.org/articles/10.3389/fphar.2024.1344042/full
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