Synthesis, biological and computational evaluation of novel cyanomethyl vinyl ether derivatives

This work explores the biological evaluation of novel cyanomethyl vinyl ether derivatives as antiproliferative agents. Tubulin, crucial to microtubule structure and function, is a target for cancer therapies. In vitro cytotoxicity assessments revealed significant activity in SKOV3 ovarian carcinoma...

Descripció completa

Dades bibliogràfiques

Autors principals:	Endika Martín-Encinas, María Fuertes, Samuel Delgado-Hernández, Fernando García-Tellado, David Tejedor, Concepción Alonso
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2024-03-01
Col·lecció:	Frontiers in Pharmacology
Matèries:	cancer chemotherapy cyanomethyl vinyl ethers cytotoxicity tubulin inhibitors
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fphar.2024.1344042/full
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!