Point mutations in c-Myc uncouple neoplastic transformation from multiple other phenotypes in rat fibroblasts.
Deregulation of c-Myc (Myc) occurs in many cancers. In addition to transforming various cell types, Myc also influences additional transformation-associated cellular phenotypes including proliferation, survival, genomic instability, reactive oxygen species production, and metabolism. Although Myc is...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science (PLoS)
2010-10-01
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| Serie: | PLoS ONE |
| Accesso online: | http://europepmc.org/articles/PMC2965668?pdf=render |
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