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Intracellular hemin is a potent inhibitor of the voltage-gated potassium channel Kv10.1

Abstract Heme, an iron-protoporphyrin IX complex, is a cofactor bound to various hemoproteins and supports a broad range of functions, such as electron transfer, oxygen transport, signal transduction, and drug metabolism. In recent years, there has been a growing recognition of heme as a non-genomic...

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Detalhes bibliográficos
Principais autores: Nirakar Sahoo, Kefan Yang, Ina Coburger, Alisa Bernert, Sandip M. Swain, Guido Gessner, Reinhard Kappl, Toni Kühl, Diana Imhof, Toshinori Hoshi, Roland Schönherr, Stefan H. Heinemann
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Portfolio 2022-08-01
Colecção:Scientific Reports
Acesso em linha:https://doi.org/10.1038/s41598-022-18975-2
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