Multimodal protein representation learning and target-aware variational auto-encoders for protein-binding ligand generation

Without knowledge of specific pockets, generating ligands based on the global structure of a protein target plays a crucial role in drug discovery as it helps reduce the search space for potential drug-like candidates in the pipeline. However, contemporary methods require optimizing tailored network...

وصف كامل

التفاصيل البيبلوغرافية

المؤلفون الرئيسيون:	Nhat Khang Ngo, Truong Son Hy
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	IOP Publishing 2024-01-01
سلاسل:	Machine Learning: Science and Technology
الموضوعات:	protein representation learning protein-ligand binding ligand generation geometric deep learning large language models multimodal architecture
الوصول للمادة أونلاين:	https://doi.org/10.1088/2632-2153/ad3ee4
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!