SCRIPT: Predicting Single‐Cell Long‐Range Cis‐Regulation Based on Pretrained Graph Attention Networks

Abstract Single‐cell cis‐regulatory relationships (CRRs) are essential for deciphering transcriptional regulation and understanding the pathogenic mechanisms of disease‐associated non‐coding variants. Existing computational methods struggle to accurately predict single‐cell CRRs due to inadequately...

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Autors principals:	Yu Zhang, Baole Wen, Yifeng Jiao, Yuchen Liu, Xin Guo, Yushuai Wu, Jiyang Li, Limei Han, Yinghui Xu, Xin Gao, Yuan Qi, Yuan Cheng, Ying He, Weidong Tian
Format:	Artigo
Idioma:	Inglês
Publicat:	Wiley 2025-11-01
Col·lecció:	Advanced Science
Matèries:	cis‐regulation graph neural networks non‐coding variant pretrain single cell
Accés en línia:	https://doi.org/10.1002/advs.202505021
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