VEGF Production Is Regulated by the AKT/ERK1/2 Signaling Pathway and Controls the Proliferation of Toxoplasma gondii in ARPE-19 Cells

The retina is the primary site of Toxoplasma gondii infection in the eye, and choroidal neovascularization in ocular toxoplasmosis is one of the most important causes of visual impairment. Vascular endothelial growth factor (VEGF) is one of the key regulators of blood vessel development, however, li...

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Detalhes bibliográficos

Principais autores:	Juan-Hua Quan, Hassan Ahmed Hassan Ahmed Ismail, Guang-Ho Cha, Young-Joon Jo, Fei Fei Gao, In-Wook Choi, Jia-Qi Chu, Jae-Min Yuk, Young-Ha Lee
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2020-04-01
coleção:	Frontiers in Cellular and Infection Microbiology
Assuntos:	ocular toxoplasmosis retinal pigment epithelium vascular endothelial growth factor PI3K/MAPK signaling pathways Toxoplasma gondii proliferation
Acesso em linha:	https://www.frontiersin.org/article/10.3389/fcimb.2020.00184/full
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