VEGF Production Is Regulated by the AKT/ERK1/2 Signaling Pathway and Controls the Proliferation of Toxoplasma gondii in ARPE-19 Cells

The retina is the primary site of Toxoplasma gondii infection in the eye, and choroidal neovascularization in ocular toxoplasmosis is one of the most important causes of visual impairment. Vascular endothelial growth factor (VEGF) is one of the key regulators of blood vessel development, however, li...

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Autors principals:	Juan-Hua Quan, Hassan Ahmed Hassan Ahmed Ismail, Guang-Ho Cha, Young-Joon Jo, Fei Fei Gao, In-Wook Choi, Jia-Qi Chu, Jae-Min Yuk, Young-Ha Lee
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2020-04-01
Col·lecció:	Frontiers in Cellular and Infection Microbiology
Matèries:	ocular toxoplasmosis retinal pigment epithelium vascular endothelial growth factor PI3K/MAPK signaling pathways Toxoplasma gondii proliferation
Accés en línia:	https://www.frontiersin.org/article/10.3389/fcimb.2020.00184/full
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