Activation of Slit2/Robo1 Signaling Promotes Tumor Metastasis in Colorectal Carcinoma through Activation of the TGF-β/Smads Pathway

Slit2 (slit guidance ligand 2), a ligand of the Roundabout1 (Robo1) transmembrane receptor, is often overexpressed in colorectal carcinomas (CRCs). In this study, we performed data mining in the Metabolic gEne RApid Visualizer (MERAV) database and found that Slit2 and TGF-β1 (Transforming growt...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Yuying Yao, Zijun Zhou, Liuyou Li, Junchen Li, Lixun Huang, Jiangchao Li, Cuiling Qi, Lingyun Zheng, Lijing Wang, Qian-Qian Zhang
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	MDPI AG 2019-06-01
Sarja:	Cells
Aiheet:	colorectal carcinoma metastasis Slit2/Robo1 signaling TGF-β/Smads signaling R5
Linkit:	https://www.mdpi.com/2073-4409/8/6/635
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