Tumour cell-expressed PD-L1 reprograms lipid metabolism via EGFR/ITGB4/SREBP1c signalling in liver cancer

Background & Aims: The programmed death-ligand 1 (PD-L1) is a major co-inhibitory checkpoint factor that controls T-cell activities in tumours. PD-L1 is expressed on immune cells and tumour cells. Whether tumour cell-expressed PD-L1 affects tumour cells in an immune cell-independent fashion rema...

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מידע ביבליוגרפי

Principais autores:	Man Zhao, Hongfeng Yuan, Guang Yang, Yufei Wang, Yanan Bu, Huihui Zhang, Lina Zhao, Pan Lv, Haolin Yun, Yu Geng, Jinyan Feng, Chunyu Hou, Shuai Wang, Ningning Zhang, Wei Lu, Xiaodong Zhang
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Elsevier 2024-04-01
סדרה:	JHEP Reports
נושאים:	PD-L1 Tumours Lipid metabolism reprogramming EGFR ITGB4 SREBP1c
גישה מקוונת:	http://www.sciencedirect.com/science/article/pii/S2589555924000107
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