Ferroptosis-induced SUMO2 lactylation counteracts ferroptosis by enhancing ACSL4 degradation in lung adenocarcinoma

Abstract Lactylation, a lactate-mediated post-translational modification, has garnered significant attention for its pivotal role in epigenetic modulation. However, the intricate interplay between lactylation and ferroptosis in lung adenocarcinoma (LUAD) remains to be fully elucidated. Utilizing met...

Description complète

Détails bibliographiques

Auteurs principaux:	Guangyao Shan, Yunyi Bian, Qihai Sui, Jiaqi Liang, Shencheng Ren, Binyang Pan, Haochun Shi, Zhaolin Zheng, Dejun Zeng, Junkan Zhu, Zhencong Chen, Guoshu Bi, Hong Fan, Cheng Zhan
Format:	Artigo
Langue:	Inglês
Publié:	Nature Publishing Group 2025-10-01
Collection:	Cell Discovery
Accès en ligne:	https://doi.org/10.1038/s41421-025-00829-6
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!