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Protein domain-level landscape of cancer-type-specific somatic mutations.

Identifying driver mutations and their functional consequences is critical to our understanding of cancer. Towards this goal, and because domains are the functional units of a protein, we explored the protein domain-level landscape of cancer-type-specific somatic mutations. Specifically, we systemat...

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Hlavní autoři: Fan Yang, Evangelia Petsalaki, Thomas Rolland, David E Hill, Marc Vidal, Frederick P Roth
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2015-03-01
Edice:PLoS Computational Biology
On-line přístup:http://europepmc.org/articles/PMC4368709?pdf=render
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