Design of quinoline SARS-CoV-2 papain-like protease inhibitors as oral antiviral drug candidates
Abstract The ever-evolving SARS-CoV-2 variants necessitate the development of additional oral antivirals. This study presents the systematic design of quinoline-containing SARS-CoV-2 papain-like protease (PLpro) inhibitors as potential oral antiviral drug candidates. By leveraging the recently disco...
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| Główni autorzy: | , , , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Nature Portfolio
2025-02-01
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| Seria: | Nature Communications |
| Dostęp online: | https://doi.org/10.1038/s41467-025-56902-x |
| Etykiety: |
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