Coronary Endothelial Dysfunction Is Associated With Elevated Serum PCSK9 Levels in People With HIV Independent of Low‐Density Lipoprotein Cholesterol

Background HIV+ people are at increased risk of coronary artery disease, but the responsible mechanisms are incompletely understood. Proprotein convertase subtilisin/kexin type 9 (PCSK9) is traditionally recognized for its importance in cholesterol metabolism; however, recent data suggest an additio...

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Autori principali:	Thorsten M. Leucker, Robert G. Weiss, Michael Schär, Gabriele Bonanno, Lena Mathews, Steven R. Jones, Todd T. Brown, Richard Moore, Yohannes Afework, Gary Gerstenblith, Allison G. Hays
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Wiley 2018-10-01
Serie:	Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Soggetti:	endothelial function HIV inflammation magnetic resonance
Accesso online:	https://www.ahajournals.org/doi/10.1161/JAHA.118.009996
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