High cell-surface density of HER2 deforms cell membranes
HER2 is frequently overexpressed in breast cancer in association with increased metastatic potential. Here, the authors show that HER2 overexpression causes deformation of cell membranes in a signalling-independent manner that contributes to the disease phenotype by disrupting epithelial features.
Na minha lista:
| Principais autores: | , , , , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Portfolio
2016-09-01
|
| coleção: | Nature Communications |
| Acesso em linha: | https://doi.org/10.1038/ncomms12742 |
| Tags: |
Sem tags, seja o primeiro a adicionar uma tag!
|