Identification and characterization of N9-methyltransferase involved in converting caffeine into non-stimulatory theacrine in tea

Kucha is a rare variety of tea tree that produces the non-stimulatory theacrine instead of caffeine. Here the authors show that theacrine synthase from Kucha has N9-methyltransferase activity resulting from amino acid substitutions that explain substrate specificity and could potentially guide produ...

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Bibliografische Detailangaben

Hauptverfasser:	Yue-Hong Zhang, Yi-Fang Li, Yongjin Wang, Li Tan, Zhi-Qin Cao, Chao Xie, Guo Xie, Hai-Biao Gong, Wan-Yang Sun, Shu-Hua Ouyang, Wen-Jun Duan, Xiaoyun Lu, Ke Ding, Hiroshi Kurihara, Dan Hu, Zhi-Min Zhang, Ikuro Abe, Rong-Rong He
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Portfolio 2020-03-01
Schriftenreihe:	Nature Communications
Online-Zugang:	https://doi.org/10.1038/s41467-020-15324-7
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