Engraftment of adult hematopoietic stem and progenitor cells in a novel model of humanized mice
Summary: Pre-clinical use of humanized mice transplanted with CD34+ hematopoietic stem and progenitor cells (HSPCs) is limited by insufficient engraftment with adult non-mobilized HSPCs. Here, we developed a novel immunodeficient mice based on NOD-SCID-Il2γc−/− (NSG) mice to support long-term engraf...
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| Glavni autori: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Elsevier
2024-03-01
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| Serija: | iScience |
| Teme: | |
| Online pristup: | http://www.sciencedirect.com/science/article/pii/S2589004224004590 |
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