Treatment strategies for Imerslund-Gräsbeck syndrome: a systematic review of vitamin B12 dosage and routes of administration

Abstract Purpose Imerslund-Gräsbeck syndrome (IGS) is a rare autosomal recessive disorder causing vitamin B12 malabsorption due to variants in CUBN or AMN. Current treatment relies on lifelong B12 supplementation, but standardized protocols are lacking. This systematic review synthesizes reported B1...

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Bibliografiset tiedot

Päätekijät:	Amina Hassan, Natasha Partab Rai, Maria Nizamani, Hamida Memon, Hussain Haider Shah
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Springer 2026-02-01
Sarja:	Journal of Rare Diseases
Aiheet:	Imerslund-Gräsbeck syndrome Vitamin B12 deficiency Cobalamin malabsorption AMN/CUBN variants Lifelong supplementation Systematic review
Linkit:	https://doi.org/10.1007/s44162-026-00168-4
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