Experimental demonstration of tethered gene drive systems for confined population modification or suppression

Abstract Background Homing gene drives hold great promise for the genetic control of natural populations. However, current homing systems are capable of spreading uncontrollably between populations connected by even marginal levels of migration. This could represent a substantial sociopolitical barr...

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主要な著者:	Matthew Metzloff, Emily Yang, Sumit Dhole, Andrew G. Clark, Philipp W. Messer, Jackson Champer
フォーマット:	Artigo
言語:	Inglês
出版事項:	BMC 2022-05-01
シリーズ:	BMC Biology
主題:	Gene drive CRISPR Toxin-antidote confined Drosophila melanogaster Tethered gene drive Population modification
オンライン･アクセス:	https://doi.org/10.1186/s12915-022-01292-5
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