Experimental demonstration of tethered gene drive systems for confined population modification or suppression

Abstract Background Homing gene drives hold great promise for the genetic control of natural populations. However, current homing systems are capable of spreading uncontrollably between populations connected by even marginal levels of migration. This could represent a substantial sociopolitical barr...

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Principais autores:	Matthew Metzloff, Emily Yang, Sumit Dhole, Andrew G. Clark, Philipp W. Messer, Jackson Champer
Format:	Artigo
Jezik:	Inglês
Izdano:	BMC 2022-05-01
Serija:	BMC Biology
Teme:	Gene drive CRISPR Toxin-antidote confined Drosophila melanogaster Tethered gene drive Population modification
Online dostop:	https://doi.org/10.1186/s12915-022-01292-5
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