Perturbation-based gene regulatory network inference to unravel oncogenic mechanisms
Abstract The gene regulatory network (GRN) of human cells encodes mechanisms to ensure proper functioning. However, if this GRN is dysregulated, the cell may enter into a disease state such as cancer. Understanding the GRN as a system can therefore help identify novel mechanisms underlying disease,...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Portfolio
2020-08-01
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| シリーズ: | Scientific Reports |
| オンライン･アクセス: | https://doi.org/10.1038/s41598-020-70941-y |
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