Differential Ca2+ handling by isolated synaptic and non-synaptic mitochondria: roles of Ca2+ buffering and efflux

Mitochondria regulate intracellular calcium ion (Ca2+) signaling by a fine-tuned process of mitochondrial matrix (m) Ca2+ influx, mCa2+ buffering (sequestration) and mCa2+ release (Ca2+ efflux). This process is critically important in the neurosynaptic terminal, where there is a simultaneous high de...

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Principais autores:	Jyotsna Mishra, Kyle Bevers, Keguo Li, Armaan Zare, James S. Heisner, Ailing Tong, Wai-Meng Kwok, David F. Stowe, Amadou K. S. Camara
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2025-05-01
coleção:	Frontiers in Synaptic Neuroscience
Assuntos:	synaptic mitochondria non-synaptic mitochondria Ca2+ buffering Ca2+ efflux bioenergetics
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fnsyn.2025.1562065/full
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