The mechanism of RNA duplex recognition and unwinding by DEAD-box helicase DDX3X
DEAD-box helicases (DDXs) function in an ATP-dependent, non-processive manner and the conserved helicase core is composed of two RecA-like domains D1 and D2. Here the authors present the crystal structure of the D1D2 core from human DDX3X bound to a 23-base pair dsRNA in the pre-unwound state and di...
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| Principais autores: | , |
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| 格式: | Artigo |
| 语言: | Inglês |
| 出版: |
Nature Portfolio
2019-07-01
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| 丛编: | Nature Communications |
| 在线阅读: | https://doi.org/10.1038/s41467-019-11083-2 |
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