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Ocular Safety of Intravitreal Engineered Humanized Anti-VEGF Nanobody and Its Efficacy in the Attenuation of Choroidal Neovascularization and Associated Subretinal Fibrosis

Current treatments for choroidal neovascularization (CNV) and its associated subretinal fibrosis (SRF), major causes of vision loss, are limited by the need for frequent intravitreal injections and the emergence of drug resistance. This study evaluated the safety and efficacy of the intravitreal adm...

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Hlavní autoři: Mir Salar Kazemi, Mozhgan Rezaei Kanavi, Fatemeh Kazemi-Lomedasht, Reza Ahangari Cohan, Golnoosh Mahjoobi, Sare Safi, Sadra Ashrafi, Hamid Ahmadieh, Alireza Shoari, Mahdi Behdani
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI AG 2026-05-01
Edice:Biomolecules
Témata:
choroidal neovascularization
subretinal fibrosis
nanobody
intravitreal injection
angiogenesis
inflammation
On-line přístup:https://www.mdpi.com/2218-273X/16/6/772
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