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Arginine Methylation Antagonizes TEAD3‐Mediated Repression to Promote Osteogenic Differentiation by Disrupting RUNX2‐Sequestrating Condensates

ABSTRACT Osteogenic differentiation is essential for bone remodeling and repair. Protein arginine methyltransferases (PRMTs) regulate this process; however, their key substrates and mechanisms remain elusive. Here, we identify TEAD3, a TEA domain transcription factor mediating Hippo signaling output...

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Príomhchruthaitheoirí: Lei Cao, Ruohui Han, Hui Xiong, Qian Li, Shaofei Tao, Xudong Wu, Dayong Liu
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: Wiley 2026-03-01
Sraith:Advanced Science
Ábhair:
Rochtain ar líne:https://doi.org/10.1002/advs.202518597
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