Arginine Methylation Antagonizes TEAD3‐Mediated Repression to Promote Osteogenic Differentiation by Disrupting RUNX2‐Sequestrating Condensates

ABSTRACT Osteogenic differentiation is essential for bone remodeling and repair. Protein arginine methyltransferases (PRMTs) regulate this process; however, their key substrates and mechanisms remain elusive. Here, we identify TEAD3, a TEA domain transcription factor mediating Hippo signaling output...

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Ngā kaituhi matua:	Lei Cao, Ruohui Han, Hui Xiong, Qian Li, Shaofei Tao, Xudong Wu, Dayong Liu
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	Wiley 2026-03-01
Rangatū:	Advanced Science
Ngā marau:	arginine methylation bone regeneration epigenetics osteogenic differentiation periodontal ligament stem cells TEAD
Urunga tuihono:	https://doi.org/10.1002/advs.202518597
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!