Systems analysis of transcription factor activities in environments with stable and dynamic oxygen concentrations

Understanding gene regulation requires knowledge of changes in transcription factor (TF) activities. Simultaneous direct measurement of numerous TF activities is currently impossible. Nevertheless, statistical approaches to infer TF activities have yielded non-trivial and verifiable predictions for...

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Detalhes bibliográficos

Principais autores:	Matthew D. Rolfe, Andrea Ocone, Melanie R. Stapleton, Simon Hall, Eleanor W. Trotter, Robert K. Poole, Guido Sanguinetti, Jeffrey Green
Formato:	Artigo
Idioma:	Inglês
Publicado em:	The Royal Society 2012-01-01
coleção:	Open Biology
Assuntos:	escherichia coli mathematical modelling oxygen-sensing systems biology transcript profiling
Acesso em linha:	https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.120091
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