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Systems analysis of transcription factor activities in environments with stable and dynamic oxygen concentrations

Understanding gene regulation requires knowledge of changes in transcription factor (TF) activities. Simultaneous direct measurement of numerous TF activities is currently impossible. Nevertheless, statistical approaches to infer TF activities have yielded non-trivial and verifiable predictions for...

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Autori principali: Matthew D. Rolfe, Andrea Ocone, Melanie R. Stapleton, Simon Hall, Eleanor W. Trotter, Robert K. Poole, Guido Sanguinetti, Jeffrey Green
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Royal Society 2012-01-01
Serie:Open Biology
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Accesso online:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.120091
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