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Are the integrin binding motifs within SARS CoV-2 spike protein and MHC class II alleles playing the key role in COVID-19?

The previous studies on the RGD motif (aa403-405) within the SARS CoV-2 spike (S) protein receptor binding domain (RBD) suggest that the RGD motif binding integrin(s) may play an important role in infection of the host cells. We also discussed the possible role of two other integrin binding motifs t...

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Hlavní autoři: Marijan Gerencer, Liam J. McGuffin
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2023-07-01
Edice:Frontiers in Immunology
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On-line přístup:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1177691/full
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