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Defining melanoma combination therapies that provide senolytic sensitivity in human melanoma cells

Malignant Melanoma that resists immunotherapy remains the deadliest form of skin cancer owing to poor clinically lasting responses. Alternative like genotoxic or targeted chemotherapy trigger various cancer cell fates after treatment including cell death and senescence. Senescent cells can be elimin...

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Hlavní autoři: Daméhan Tchelougou, Nicolas Malaquin, Guillaume B. Cardin, Jordan Desmul, Simon Turcotte, Francis Rodier
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2024-06-01
Edice:Frontiers in Cell and Developmental Biology
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On-line přístup:https://www.frontiersin.org/articles/10.3389/fcell.2024.1368711/full
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