Defining melanoma combination therapies that provide senolytic sensitivity in human melanoma cells

Malignant Melanoma that resists immunotherapy remains the deadliest form of skin cancer owing to poor clinically lasting responses. Alternative like genotoxic or targeted chemotherapy trigger various cancer cell fates after treatment including cell death and senescence. Senescent cells can be elimin...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Daméhan Tchelougou, Nicolas Malaquin, Guillaume B. Cardin, Jordan Desmul, Simon Turcotte, Francis Rodier
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Frontiers Media S.A. 2024-06-01
Цуврал:	Frontiers in Cell and Developmental Biology
Нөхцлүүд:	senescence senescence-like Bcl2/BclxL inhibitors senolytic BRAFi MEKi
Онлайн хандалт:	https://www.frontiersin.org/articles/10.3389/fcell.2024.1368711/full
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!