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Cytometric proteome profiling of GFP-tagged yeast for characterizing novel antifungals

Abstract Assaying cellular responses to antimicrobial molecules is one way to understand modes of action of potential drugs. This is often achieved via transcriptomics and proteomics, but simple, inexpensive methods for rapid characterization are lacking. To bridge this gap, we assayed changes in th...

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Autori principali: Eslam Ghazy, Victoria A. Bidiuk, Fedor Ryabov, Olga V. Mitkevich, Olga B. Riabova, Yaroslav M. Stanishevskiy, Igor B. Levshin, Liudmila A. Alexandrova, Maxim V. Jasko, Dmitriy A. Makarov, Alexander A. Zhgun, Darya A. Avdanina, Anna A. Ermolyuk, Vitaly V. Kushnirov, Anna P. Egorova, Michael O. Agaphonov, Alexander I. Alexandrov
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Portfolio 2026-04-01
Serie:Communications Biology
Accesso online:https://doi.org/10.1038/s42003-026-10083-5
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