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Paused RNA polymerase primes promoters via RNA-mediated stabilisation of transcription factor ERα

Abstract Regulated pausing of RNA polymerase II (Pol II) is essential for enabling rapid and coordinated transcriptional responses to signalling cues. Pausing also contributes to the formation of nucleosome-free regions with the help of chromatin remodellers. However, if these nucleosome-free region...

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Príomhchruthaitheoirí: Rajat Mann, Deepanshu Soota, Ayan Das, Nitesh Kumar Podh, Gunjan Mehta, Dimple Notani
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: Nature Portfolio 2025-10-01
Sraith:Nature Communications
Rochtain ar líne:https://doi.org/10.1038/s41467-025-64569-7
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