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Paused RNA polymerase primes promoters via RNA-mediated stabilisation of transcription factor ERα

Abstract Regulated pausing of RNA polymerase II (Pol II) is essential for enabling rapid and coordinated transcriptional responses to signalling cues. Pausing also contributes to the formation of nucleosome-free regions with the help of chromatin remodellers. However, if these nucleosome-free region...

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Bibliografiske detaljer
Principais autores: Rajat Mann, Deepanshu Soota, Ayan Das, Nitesh Kumar Podh, Gunjan Mehta, Dimple Notani
Format: Artigo
Sprog:Inglês
Udgivet: Nature Portfolio 2025-10-01
Serier:Nature Communications
Online adgang:https://doi.org/10.1038/s41467-025-64569-7
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