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Influence of an immunodominant herpes simplex virus type 1 CD8+ T cell epitope on the target hierarchy and function of subdominant CD8+ T cells.

Herpes simplex virus type 1 (HSV-1) latency in sensory ganglia such as trigeminal ganglia (TG) is associated with a persistent immune infiltrate that includes effector memory CD8+ T cells that can influence HSV-1 reactivation. In C57BL/6 mice, HSV-1 induces a highly skewed CD8+ T cell repertoire, in...

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Váldodahkkit: Benjamin R Treat, Sarah M Bidula, Srividya Ramachandran, Anthony J St Leger, Robert L Hendricks, Paul R Kinchington
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Public Library of Science (PLoS) 2017-12-01
Ráidu:PLoS Pathogens
Liŋkkat:http://europepmc.org/articles/PMC5736228?pdf=render
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