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Empowered pro-inflammatory features in Ly6C monocytes and altered antigen-presenting capacity in Ly6Chigh monocytes in diabetic mice

RationaleInflammatory monocyte (MC) subset polarization is a hallmark of systemic and tissue inflammatory feature in diabetes. The underlying molecular mechanism remains unclear.Methods and resultsBlood pro-inflammatory Ly6Chigh and anti-inflammatory Ly6Clow MC subsets were isolated from control (C5...

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Principais autores: Pingping Yang, Pu Fang, Lizhe Sun, Lu Liu, Linghua Fu, Hang Xi, Xianwei Wang, Rihab Bouchareb, Daqing Zhang, Qinghua Wu, Yong Ji, Xiaofeng Yang, Hong Wang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2026-05-01
coleção:Frontiers in Immunology
Assuntos:
cytokine
diabetes
immune checkpoint
inflammatory
Ly6C monocyte
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2026.1794704/full
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