Refphase: Multi-sample phasing reveals haplotype-specific copy number heterogeneity.
Most computational methods that infer somatic copy number alterations (SCNAs) from bulk sequencing of DNA analyse tumour samples individually. However, the sequencing of multiple tumour samples from a patient's disease is an increasingly common practice. We introduce Refphase, an algorithm that leve...
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| Principais autores: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science (PLoS)
2023-10-01
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| coleção: | PLoS Computational Biology |
| Acesso em linha: | https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1011379&type=printable |
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