Haplotype-aware segmentation with HapASeg increases accuracy of detecting homolog-specific somatic copy number alterations
Abstract Somatic copy number alterations (sCNAs) drive cancer initiation, progression, resistance, and metastasis. Furthering our understanding of sCNAs requires substantially larger cohorts. Most tumors available for sequencing are preserved with formalin-fixed, paraffin-embedding (FFPE), which cau...
I tiakina i:
| Ngā kaituhi matua: | , , , , , |
|---|---|
| Hōputu: | Artigo |
| Reo: | Inglês |
| I whakaputaina: |
BMC
2026-02-01
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| Rangatū: | Genome Biology |
| Ngā marau: | |
| Urunga tuihono: | https://doi.org/10.1186/s13059-026-03971-w |
| Ngā Tūtohu: |
Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!
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