Immune microenvironment spatial landscapes of tertiary lymphoid structures in gastric cancer

Abstract Background Tertiary lymphoid structures (TLS) correlate with tumour prognosis and immunotherapy responses in gastric cancer (GC) studies. However, understanding the complex and diverse immune microenvironment within TLS requires comprehensive analysis. Methods We examined the prognostic imp...

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Principais autores:	Yi Xie, Haoxin Peng, Yajie Hu, Keren Jia, Jiajia Yuan, Dan Liu, Yanyan Li, Xujiao Feng, Jian Li, Xiaotian Zhang, Yu Sun, Lin Shen, Yang Chen
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2025-02-01
Series:	BMC Medicine
Assuntos:	Gastric cancer Tertiary lymphoid structures Tumour microenvironment Immunotherapy Prognostic model Single-cell RNA sequencing
Acceso en liña:	https://doi.org/10.1186/s12916-025-03889-3
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