Immune microenvironment spatial landscapes of tertiary lymphoid structures in gastric cancer

Abstract Background Tertiary lymphoid structures (TLS) correlate with tumour prognosis and immunotherapy responses in gastric cancer (GC) studies. However, understanding the complex and diverse immune microenvironment within TLS requires comprehensive analysis. Methods We examined the prognostic imp...

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Autori principali:	Yi Xie, Haoxin Peng, Yajie Hu, Keren Jia, Jiajia Yuan, Dan Liu, Yanyan Li, Xujiao Feng, Jian Li, Xiaotian Zhang, Yu Sun, Lin Shen, Yang Chen
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2025-02-01
Serie:	BMC Medicine
Soggetti:	Gastric cancer Tertiary lymphoid structures Tumour microenvironment Immunotherapy Prognostic model Single-cell RNA sequencing
Accesso online:	https://doi.org/10.1186/s12916-025-03889-3
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