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The role of conserved waters in conformational transitions of Q61H K-ras.

To investigate the stability and functional role of long-residence water molecules in the Q61H variant of the signaling protein K-ras, we analyzed all available Ras crystal structures and conformers derived from a series of independent explicit solvent molecular dynamics (MD) simulations totaling 1....

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Priyanka Prakash, Abdallah Sayyed-Ahmad, Alemayehu A Gorfe
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Public Library of Science (PLoS) 2012-01-01
Rangatū:PLoS Computational Biology
Urunga tuihono:http://europepmc.org/articles/PMC3280954?pdf=render
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