The role of conserved waters in conformational transitions of Q61H K-ras.
To investigate the stability and functional role of long-residence water molecules in the Q61H variant of the signaling protein K-ras, we analyzed all available Ras crystal structures and conformers derived from a series of independent explicit solvent molecular dynamics (MD) simulations totaling 1....
Gardado en:
| Principais autores: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science (PLoS)
2012-01-01
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| Series: | PLoS Computational Biology |
| Acceso en liña: | http://europepmc.org/articles/PMC3280954?pdf=render |
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