Pathological β-Cell Endoplasmic Reticulum Stress in Type 2 Diabetes: Current Evidence

The notion that in diabetes pancreatic β-cells express endoplasmic reticulum (ER) stress markers indicative of increased unfolded protein response (UPR) signaling is no longer in doubt. However, what remains controversial is whether this increase in ER stress response actually contributes importantl...

Descripció completa

Dades bibliogràfiques

Autors principals:	Neha Shrestha, Elisa De Franco, Peter Arvan, Miriam Cnop
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2021-04-01
Col·lecció:	Frontiers in Endocrinology
Matèries:	endoplasmic reticulum stress unfolded protein response insulin PERK (PKR-like endoplasmic reticulum kinase) ATF6 (activating transcription factor 6)
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fendo.2021.650158/full
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!