Endoplasmic reticulum stress associates with the development of intervertebral disc degeneration

Endoplasmic reticulum (ER) is an important player in various intracellular signaling pathways that regulate cellular functions in many diseases. Intervertebral disc degeneration (IDD), an age-related degenerative disease, is one of the main clinical causes of low back pain. Although the pathological...

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Bibliografische Detailangaben

Hauptverfasser:	Jishang Huang, Qingluo Zhou, Qun Ren, Liliang Luo, Guanglin Ji, Tiansheng Zheng
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2023-01-01
Schriftenreihe:	Frontiers in Endocrinology
Schlagworte:	intervertebral disc degeneration endoplasmic reticulum stress apoptosis PERK IRE1α ATF6
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fendo.2022.1094394/full
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