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Fundamental Characterization of Antibody Fusion-Single-Chain TNF Recombinant Proteins Directed against Costimulatory TNF Receptors Expressed by T-Lymphocytes

The costimulatory signal regulated by the members of the tumor necrosis factor receptor (TNFR) superfamily expressed by T cells plays essential roles for T cell responses and has emerged as a promising target for cancer immunotherapy. However, it is unclear how the difference in TNFR costimulation c...

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Principais autores: Hodaka Nagai, Mitsuki Azuma, Ayaka Sato, Nagito Shibui, Sayaka Ogawara, Yuta Tsutsui, Ayano Suzuki, Tomomi Wakaizumi, Aya Ito, Shimpei Matsuyama, Masashi Morita, Mari Hikosaka Kuniishi, Naoto Ishii, Takanori So
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2023-06-01
coleção:Cells
Assuntos:
4-1BB
CD27
costimulation
GITR
OX40
T cell
Acesso em linha:https://www.mdpi.com/2073-4409/12/12/1596
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