OX40/OX40L: a new target for tumor immunotherapy and its clinical research progress
TNFRSF4 (OX40) -TNFSF4 (OX40L) axis is the core costimulatory pathway in the TNF/TNFR superfamily that regulates T cell responses. The binding of OX40L to OX40 on the surface of activated T cells significantly enhanced the proliferation and survival of CD4+ and CD8+ T cells and the secretion of IFN-...
Enregistré dans:
| Auteurs principaux: | , , , |
|---|---|
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Frontiers Media S.A.
2026-01-01
|
| Collection: | Frontiers in Oncology |
| Sujets: | |
| Accès en ligne: | https://www.frontiersin.org/articles/10.3389/fonc.2025.1730620/full |
| Tags: |
Pas de tags, Soyez le premier à ajouter un tag!
|