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Marginal zone B cells mediate humoral immunity in vaccine-induced versus naturally acquired immunity against SARS-CoV-2

Abstract The role of marginal zone B (MZB) cells in SARS-CoV-2 immunity remains unclear, particularly in comparing vaccine-induced responses to natural infection. MZB cells are crucial for rapid antibody responses, but their contributions to vaccine-induced immunity, especially in the elderly, are n...

Cur síos iomlán

Sábháilte in:
Príomhchruthaitheoirí: Jie Shu, Jiameng Yao, Meiyu Tan, Hanxiao Sun, Xiaohui Wu, Fengjun Chen, Binbin Xuan, Chenfei Du, Yunqi Pan, Lida Zhou, Hong Li, Yajie Wang, Chenxin Gan, Shengce Tao, Jinpiao Lin, Huiming Sheng
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: Nature Portfolio 2026-02-01
Sraith:Scientific Reports
Ábhair:
Marginal zone B cells
SARS-CoV-2
Inactivated wholevirus
Vaccine
B cell receptor repertoire
Rochtain ar líne:https://doi.org/10.1038/s41598-026-38298-w
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