Identification and clinicopathological analysis of potential p73-regulated biomarkers in colorectal cancer via integrative bioinformatics

Abstract This study aims to decipher crucial biomarkers regulated by p73 for the early detection of colorectal cancer (CRC) by employing a combination of integrative bioinformatics and expression profiling techniques. The transcriptome profile of HCT116 cell line p53 $$^{-/-}$$ - / - p73 $$^{+/+}$$...

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Hlavní autoři:	Chanchal Bareja, Kountay Dwivedi, Apoorva Uboveja, Ankit Mathur, Naveen Kumar, Daman Saluja
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2024-04-01
Edice:	Scientific Reports
Témata:	Transcriptomics Integrative bioinformatics P53 P73 TNM stage Gene expression omnibus
On-line přístup:	https://doi.org/10.1038/s41598-024-60715-1
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